电灼术联合干扰素封闭治疗肛周尖锐湿疣的疗效评价-中国医院药学杂志.PDF

第 31 卷 第 5 期 医 学 研 究 与 教 育 Vol. 31 No. 5 2014 年 10 月 Medical Research and Education Oct., 2014 电灼术联合干扰素封闭治疗肛周尖锐湿疣的疗效评价 赵桂香，张红岩，王永强，刘春梅，鲁楠 （河北大学附属医院，河北 保定 071000） 摘要： 目的 评价电灼术联合干扰素封闭治疗肛周尖锐湿疣的疗效。 方法 采用电灼术联合局部干扰素封闭治疗肛周尖锐 湿疣 51 例 ( 观察组 )，单纯应用电灼术治疗肛周湿疣 51 例（对照组），比较一次性痊愈率和 12 周复发情况。 结果 观察 组比对照组治愈率高（P0.05），观察组 12 周复发明显少于对照组（P0.05）。 结论 电灼术联合干扰素封闭治疗肛周尖 锐湿疣治愈率高，复发率低，能明显减轻患者的痛苦，患者易于接受。 关键词：电灼术；干扰素；肛周尖锐湿疣 中图分类号：R75 文献标志码：A 文章编号：1674-490X(2014)05-0019-03 Evaluation of local blocking treatment efficiency of perianal condyloma through fulguration in combination with interferon ZHAO Guixiang, ZHANG Hongyan, WANG Yongqiang, LIU Chunmei, LU Nan (Affiliated Hospital of Hebei University, Baoding 071000, China) Abstract: Objective To evaluate enclosed treatment efficiency of perianal condyloma through fulguration in combination with interferon. Methods 51 cases with perianal warts (study group) were treated with fulguration combined with local interferon, 51 cases (control group) were treated with fulguration to compare one-time cure rate and the recurrence after treating for 12 weeks. Results The cure rate of the observation group was higher than that of the control group (P0.05), the recurrence rate of observation group was significantly less than of the control group (P0.05). Conclusion The cure rate of perianal condyloma treated with fulguration in combination with interferon is high, the recurrence rate is low, the therapy can significantly alleviate the suffering of patients, which can be easily accepted by patients. Key words: fulguration; interferon; perianal condyloma 尖锐湿疣（condyloma acuminatum，CA）是人类乳头瘤病毒（human papillary virus，HPV）感染引起 的皮肤黏膜增生性病变，主要通过性接触传播，HPV 在人体温暖潮湿的条件下最宜生存繁殖，故外生 殖器及肛周部位最易发生感染[1] ，随着社会的发展，人们的性观念逐渐开放和同性恋的增多，使得尖锐 湿疣的发病率逐渐升高[2] ，且复发率高。为了探索治疗肛周 CA 的有效方法，皮肤科自 2010