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主动脉瓣疾(国外英文资料)
主动脉瓣疾
The second aortic valve disease
One, aortic stenosis
[etiology and pathology]
(1) wind and heart
Rheumatoid inflammation leads to adhesion fusion at the junction of the valve, and the flap is narrowed by fibrosis, stiffness, calcification and contracture. There is almost no pure rheumatic aortic stenosis, with mostly closed and mitral damage.
(2) congenital malformation
The cause of the most common congenital aortic stenosis. Congenital bilobes were found in 1% to 2% of the population, more men than women. At birth, there is no border of fusion and narrowing. Due to the abnormality of the leaf structure, even normal blood flow dynamics can cause the valve to thicken, calcify, stiffen and stenosis, and about a third of the stenosis. The common cause of adult isolated aortic stenosis is the formation of elliptical or narrow-seam stenosis in adulthood. Bicuspid aortic valve disc deformities complicated with infective endocarditis, and aortic valve infective endocarditis, the most common heart disease as the basis of two lobes deformity.
Other congenital aortic valve deformities are rare, and the flap is eccentric, with a circular or teardrop, and is born with a stenosis. If the stenosis starts with light, it increases the stenosis of progressive calcification in adulthood. Three (2) congenital bicuspid valves are very rare, narrow range for three more disc leaves large, may be born with narrow, may also after the middle-aged flap gradually fibrosis and calcification in valvular stenosis.
(3) the narrowing of the aortic valve stenosis of the degenerative elderly
Common causes of simple aortic stenosis in older people over 65 years of age. There is no junction, and there is calcified nodules on the aorta. It is often accompanied by mitral ring calcification.
[pathological physiology]
The adult aortic valve is greater than 3.0cm 2. When the area of the flap is reduced by one and a half, the systolic is still not significant. At less than 1.0 cm 2, the left ventri
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