淋巴瘤空泡状细胞核识别提取研究.pdf

淋巴瘤空泡状细胞核识别提取研究.pdf

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2004 9 4 193 CHINESEJOURNALOF STEREOLOGY AND IMAGEANALYSIS Vol19 No14 Sept12004 : 1007- 14 2(2004) 04- 0193- 06 ## 1 1 2 , , ( 11 , 350002; 21 , 350025) =: :介绍了一种自动提取淋巴瘤病理图像中空泡状细胞核方法: 以空泡状细胞核为 目标,采用 CMYK 模式下的多层分割法分割病理图像; 提出变尺寸特征窗口模糊分类法, 对空 泡状细胞核进行识别提取; 并用近似最短连接法对破碎的空泡核进行修补连接: 实验结果表 明, 该方法可以有效对淋巴瘤病理图像进行分割,较准确地提取空泡状细胞核, 并具有一定程度的 自动修补连接破碎细胞核能力 =: 空泡状细胞核; CMYK 模式;分割;模糊分类; 复原 = :TP312 =: A Recognition and Extraction of Lymphoma Vacuole Nucleus 1 1 2 YANG Dian- qing , LIU Bing- han , ZH NG Zhi- yong ( 11 College of Mathematics and Computer Science Fuzhou University, Fuzhou, 350002 21 Pathological Section, Fuzhou Chief Hospital, Nanjing Military Region, Fuzhou, 350025) =A STRACT: Objective: A new method is introduced to extract vacuole nucleus in the lymphoma pathologic image automatically. Method: With vacuole nucleus as the subject, use multilayer segmen- tation algorithm to segment pathologic images in the CMYK mode. Use a fuzzy classification with dy- namic size feature windows to recognize and extract vacuole nucleus. In the meantime, restore and connect broken vacuole nucleuses with approximately nearest connection algorithm. Conclusion: The results of these experiments show that this method can effectively segment lymphoma pathologic im- ages, comparatively accurately extract vacuole nucleuses, and, to some degree, be able to restore and connect broken nucleuses automatically. =KEYWORDS: vacuole nucleus; CMYK mode; segmentation; fuzzy classification; restoration

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