一个可能引起歧义的概念.PDF

微生物学通报 OCT 20, 2011, 38(10): 1584−1586 Microbiology China © 2011 by Institute of Microbiology, CAS tongbao@ 高校教改纵横 一个可能引起歧义的概念 ——“条件致病菌”辨析 * 孙锦霞 王易 刘丹 王莉新 (上海中医药大学 免疫学与病原生物学教研室 上海 201203) 摘 要: “条件致病菌”是国内医学微生物学教材中普遍应用的一个基本概念, 但此概念在建立与 应用中都存在明显缺陷, 其使用可能对医学学生理解“人体共生微生物群落”与“机会性感染”等重 要的医学基础理念造成误解与歧义。谨就此提出一些粗浅的认识与观点, 希望通过同行间切磋, 就此建立更完善的概念与更合理的表述。 关键词: 条件致病菌, 正常菌群, 机会性感染 An ambiguous concept: clarification on conditioned pathogen * SUN Jin-Xia WANG Yi LIU Dan WANG Li-Xin (Department of Pathogenic Biology , Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China) Abstract: Conditioned pathogen was a basic concept widely used in domestic medical microbiology textbook. However, there were obvious defects both in the establishment and application of this con- cept. And which might make students misunderstand and be ambiguous when learn some essential fun- dermental cocepts, such as symbiotic microbial community in the human body and conditioned patho- gen. So here we offer some initial ideas for discussion, and hope a more faultless and suitable formula- tion could be made by learning from each other. Keywords: Conditioned pathogen, Normal flora, Opportunistic infections “条件致病 ”是国内医学微生物学教材中普遍 可被打破而引起疾病”这样一种状态 [3−4] , 该状态下 出现的一个概念。这一概念的提出可以追溯至 20 引起疾病的“正常菌群”就称为“条件致病菌” 。这个 世 纪 七 八