重症患者的胰岛素强化治疗-培训课件.pptVIP

Four prior published studies have observed at least some reduction in mortality associated with IIT in critically ill patients. 1. Van den Berghe reported the results of a large randomized trial of IIT in patients admitted to a surgical ICU, approximately 60% of whom had undergone cardiac surgery. IIT (blood glucose 80 to 110 mg/dL) was associated with a reduction in mortality from 8.0% to 4.6% 2. In a subsequent study, van den Berghe randomly assigned patients admitted to a medical ICU to IIT or conventional blood glucose management. There was no clear mortality benefit for IIT in the intent