直肠癌术后同时性肝肺转移个体化治疗个案分析-Untitiled.PDFVIP

2012年第39卷第20期 中国肿瘤临床 1559 · · 临床病例讨论 直肠癌术后同时性肝肺转移个体化治疗的 个案分析* ① ② ③ ④ ⑤ ⑥ 陈 平 尤 健 黄鼎智 袁智勇 肖建宇 张连郁 ⑦ ⑧ ① 郭 志 曹付亮 宋天强 摘要 结直肠癌肝转移患者自然生存时间为6～12个月，同时伴有肺转移的生存时间更短。单纯化疗后可延长至12～24 个月。对于结直肠癌肝转移患者，绝大多数死于肝脏的病灶。结直肠癌肝转移行肝切除术者，5年生存率大约40%。根治性手术 切除是治疗结直肠癌肝转移的最佳方法，放化疗亦具有重要价值。现介绍1例天津医科大学附属肿瘤医院经肝胆肿瘤科、肺部肿 瘤科治疗的直肠癌术后同时性肝肺转移的病例，该患者经多学科的协作诊疗后效果较佳，报道该病例诊治经验以促进结直肠癌 诊疗技术和经验的全面融合，推动多学科间的交流与合作。 关键词 结直肠癌 肝转移 肺转移 个体化治疗 多学科协作诊疗模式 doi:10.3969/j.issn.1000-8179.2012.20.026 A Case Analysis of Rectal Cancer with Synchronous Hepatic and Pulmonary Metastases with Individualized Therapy 1 2 3 4 5 6 7 8 1 Ping CHEN , Jian YOU , Dingzhi HUANG , Zhiyong YUAN , Jianyu XIAO , Lianyu ZHANG , Zhi GUO , Fuliang CAO , Tianqiang SONG Correspondence to: Tianqiang SONG; Email: songtianqiang@ 1Department of hepatobiliary surgery, 2Department of lung cancer, 3Department of gastrointestinal oncology, 4Department of radiothera- py, 5Department of radiology, 6Department of pathology, 7Department of interventional therapy, 8Endoscopy center, Tianjin Key Labora- tory of Cancer prevention and therapy, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China National Basic Research Program of China (973 program) (Project number: 2011CB933100) Abstract Objective: The overall survival time of colorectal cancer patients with hepatic metastasis is 6 months to 12 months, and is shorter in patients wit