腔内激光和贝复、长效青霉素联合应用治疗合并慢性溃疡的下肢静脉曲张的临床研究.docVIP

腔内激光、贝复济及长效青霉素联合应用治疗合并慢性溃疡的下肢静脉曲张的临床研究 鉴涛 王旭 济宁市第一人民医院 血管外科（山东 济宁 272000） 摘要 目的 探讨血管腔内激光、贝复济及长效青霉素联合应用治疗合并慢性溃疡的下肢静脉曲张的远期疗效。方法 回顾性分析2006年8月至2008年1月应用腔内激光联合贝复济及长效青霉素治疗的40例下肢静脉曲张合并慢性溃疡的患者，其临床治疗效果与2005年8月至2006年7月应用传统的高位结扎加剥脱的手术方法治疗的38例下肢静脉曲张合并慢性溃疡的患者作对比分析。结果 两组慢性溃疡治愈率及创面愈合时间比较，差异均有统计学意义(P＜0.05)。结论 腔内激光治疗下肢浅静脉曲张是一种有效、简便且安全的微创技术，贝复济联合长效青霉素的使用使溃疡创面更快愈合，并能减少复发率。 关键词 静脉曲张 腔内激光治疗 贝复济 长效青霉素 Clinical study on treatment of endovenous laser combined with bFGF and benzathine penicillin for varicose vein of lower limb with chronic ulcer. JIAN Tao,WANG Xu.Department of Vascular surgery, SHANDONG JINING NO.1 PEOPLE’S HOSPITAL,Jining,272000, China. Abstract Objective To explore the long-time effects of endovenous laser combined with bFGF and benzathine penicillin in treating varicose vein of lower limb with chronic ulcer.Method Between August,2006,and January, 2008,40 patients of varicose vein of lower limb with chronic ulcer were Performed with endovenous laser combined with bFGF and benzathine penicillin,which clinical curative effect were comparatively analysised of 38 patients(between August,2005,and July,2006) of varicose vein of lower limb with chronic ulcer were performed with ligation?of great saphenous vein and denudation of superficial varicosities. Results The differences?of the healing rate and time of chronic ulcer were had statistical significance (P 0.05). Conclustion Endovenous laser treatment of varicose vein of lower limb is an effective, simple and safe minimally invasive techniques, the useing of?bFGF and benzathine penicillin makes the ulcer healing faster, and reducing the recurrence rate. Keywords? Varicose vein of lower limb Endovenous laser treatment bFGF benzathine penicillin 下肢静脉曲张（varicose veins of lower extremity）是临床上最常见的有较高发病率的静脉疾病，据欧洲文献报道，其发生率在男性中占15％，在女性中占25％[1]。WHO对其定义为：浅静脉局限性、节段性囊状或圆柱状扩张，可合并各种静脉性皮肤病变，病程长，传统治疗效果欠佳，病情反复影响美观及生活。我们采用腔内激光治疗，并辅助使用贝复济、长效青霉素治疗下肢浅静脉曲张合并慢性溃疡的患者，取得了良好的疗效，现报告如下。 1.资料与方法 1.1一般资料 实验组40例患者（49条患肢），其中男25例/30肢，女15例/19肢；年龄35～72岁，平