贵州省708例尿路结石成分分析-第三军医大学学报.docVIP

贵州省708例尿路结石成分分析 石 华1，*，徐述雄2，*，李 凯2，王晓东2，王元林1，孙兆林2，熊鸿燕1 （400038 重庆，第三军医大学军事预防医学院军队流行病学教研室1；550002 贵阳，贵州省人民医院泌尿外科2） [摘要] 目的分析的化学成分方法回顾性人民医院泌尿外科2009年月至201年月共例病例以红外光谱法分析结石的化学成分并结果结论的化学成分stone composition in Guizhou province Shi Hua1，*, Xu Shuxiong2，*, Li Kai2, Wang Xiaodong2, Wang Yuanlin2, Sun Zhaolin2, Xiong Hongyan1，# (1Department of Epidemiology, Faculty of Military Prevention Medicine, Third Military Medical University, Chongqing, 400038, China; 2Department of Urology, Guizhou Provincial People’s Hospital, Guiyang, Guizhou province, 550002, China) [Abstract] Objective The aim of this study was to evaluate the biochemical stone composition in general population of Guizhou province, and provide theoretic rationales for prevention of urolithiasis. Methods In a prospective study, from December 2009 to September 2012, biochemical analysis of urinary stones in patients living in Guizhou province was performed by infrared spectrophotometry. Most of the stones were retrieved by endoscopic or open surgery. Some had been passed spontaneously or by extracorporeal shock wave lithotripsy. Gender, age and stone location of patients were evaluated and compared with biochemical stone analysis. Results Stone analysis was performed in 708 patients. The most dominant composition of urinary stones was calcium oxalate (94.77%), followed by carbonate apatite (38.1%), uric acid or ammonium urate (13.41%), ammonium magnesium phosphate (3.53%), calcium hydrophosphate (0.56%), and cystine (0.28%). Overall male to female ratio was 1.97:1. The peak incidence of urinary stone was in patients in their forties to sixties. Conclusion The dominant stone composition in inhabitants of Guizhou province was calcium oxalate stones, which differs from other regions of China. Some special measures to calcium oxalate should be taken to prevent urolithiasis in Guizhou province. [Key words] stone analysis, urinary stones, stone composition Supported by National Natural Science Foundation of C