CC趋化因子(外国英文资料).docVIP

CC趋化因子(国外英文资料) Chemokine CC the family Other name: English name: chemokine CC subfamily beta the family definition: molecular n-terminal contains two adjacent Cys residue, has more than 20 members, mainly chemotaxis and activation of mononuclear cells and some T cell subsets, also can affect activated B cells, and eosinophils, DC and NK cells, neutrophils no effect. Dendritic Cells (DC), DC, are the most closely watched occupational Antigen presenting Cells in recent years Cells, APC), can ingest, process, and present antigen, initiate t-cell-mediated immune response. DC was first discovered by Steinman and Cohn in 1973. After a long time, due to limited by biology technology at that time, people cant nurture more of dendritic cells in vitro, and the price is expensive, the result is failed to further research on it. Enter in the ninety s, people take in biology technology improved, can cultivate dendritic cells in vitro, and the research of DC also there will be a breakthrough. At the end of the 20th century, the United States was the first in the United States to begin the trial of dendritic cell immune-treating tumours in humans. The results are encouraging. Then came the fact that dendritic cells became the star of cancer treatment, and became a hot topic for scientists around the world to fight cancer. In the 21st century, scientists at home and abroad have found that DC plays an important role in treating asthma and other diseases. Dendritic cells are the bodys immune system sentry, it can be keen to capture the tumor cells and normal cells that small differences, and convey the difference to the armed police - T cells in the bodys immune system, let T lymphocytes to accept to identify insurgents method and combat command, the resting state rapidly into combat, all remaining and metastasis of cancer cells in the human body, thoroughly clean. And T cell immune ability and memory, that is to say, ones life in the same cancer cells, the bodys immune system will