乳腺浸润性小叶癌临床病理分析.docVIP

乳腺浸润性小叶癌的临床病理分析 Clinical Pathological Analysis of Puncture Biopsy Breast Cancer (PBBC) 中文摘要 Abstract [目的]：分析乳腺浸润性小叶癌患者的临床病理特征，探讨乳腺浸润性小叶癌的疾病规律和特点。 [Target]: Analyze the clinical pathological of patients who suffer PBBC (Puncture Biopsy Breast Cancer), and discuss the rules and characteristics of PBBC. [材料和方法]：2001年1月至2008年12月间在我院经过手术治疗，经病理证实为原发乳腺浸润性小叶癌患者68例。统计患者年龄分布、月经状况、肿瘤位置、超声检查、X线钼靶摄片检查、TNM分期以及免疫组化等临床特点和肿瘤病理特点，并与乳腺浸润性导管癌相关资料进行比较和分析。 [Information and Methods]: between January 2001 and December 2008, 68 patients who had operation in our hospital are diagnosed to be suffering PBBC. The writer statistics these patients’ information on a series of clinical features and pathology features including age, menstruation condition, position of tumor, ultrasonic examination, molybdenum target X-ray, TNM period, and Envision TM, and then compare and analyze the features with other PBBC documents. [结果]：乳腺浸润性小叶癌的发病高峰年龄在40-49岁，共29例（42.7%）；其次是50-59岁，16例（23.5%）。其中年龄最小者30岁，最大者79岁，平均年龄50.2岁；绝经前病人共39例（57.4%），已绝经29例（42.6%）；原发肿瘤发生在左侧乳腺的有31例（45.6%）: peak age of PBBC is between 40 and 49, which period has 29 patients (42.7%); then following the age between 50 and 59, which has 16 patients (23.5%). The youngest patient is 30 years old while the eldest is 79.The average age of the tested people are 50.2. 39 women (57.4%) does not menopause, and 29 women (42.6%) reach menopause already. 35 cases (45.6%) occurs on the left breast, 35 cases (51.5) occurs on the right side, and 2 cases (2.9%) occurs on both sides. Most cases (27 cases, 45% of the overall cases) start from the outer upper guardant. Four patients have positive effect on ultrasonic examination before operation, 11 out of 12 in molybdenum target X-ray (91.7%). According to the AJCC TNM, the figures are: 8 cases (12.9%) in period I, 37 (59.7%) in period II, 17(27.4%) in period III; Envision TM is as follows: 55 cases ER+ (87.3%), 56 cases PR+ (88.9%), 14 cases HER-2+ (22.2%).There is no different between ILC and IDC with patients’ a