预防医学课件7地方病.ppt

三、主要病因与发病机制 目前对地方性氟病的发病机理尚未完全阐明，可能有三方面原因： （一）过量的氟影响钙磷代谢 （二）过量的氟对牙齿的损害 （三）过量的氟抑制体内某些酶的活性 四、临床表现与诊断 （一）氟斑牙 氟斑牙（dental fluorosis） 是氟中毒的早期表现。 临床上把氟斑牙分为三型 ①白垩型 ②着色型 ③缺损型 Common causes of fluorosis include: inhalation of fluoride dusts/fumes by workers in industry, use of coal as an indoor fuel source (a common practice in China), and consumption of fluoride from drinking water. Small opaque, paper white areas scattered irregularly over the tooth but not involving as much as 25 percent of the tooth surface.“ (Dean 1942) Very Mild Deans Classification Criteria for Dental Fluorosis T