Lung cancer概要1.ppt

Lung cancer(types and presentation) Presented by Reem alssafar Bronchial carcinoma .most common fatal lung malignancy account for 95% of lung cancer .leading cause of cancer death. .peak incidence occur between ages 55-65 years . .there is a 3:1 male : female ratio. . Aetiology : - smoking is the most common aetiological factor. -others: passive smokers , exposure to asbestos, chromium , iron oxide and products of cool combustion Types: There are 4 major types : 1- epidermiod [squamous] -35% 2- adeno carinema -30% 3- large cell carcinoma -15% 4- small cell lung cancer -20% Epidermiod carcinoma -35% : .occurs most frequently in men and old people .usually starts on one breathing tubes. .tend to be localized in the chest longer than other types of lung cancer. .does not tend to metastasize early. .It is strongly associated with smoking. Adenocarcinnoma-30%: .most common cancer among women. .usually started near the outer edges of the lung. .Invasion of pleura and mediastinal lymph node is common. .may spread to other parts of the body. .can be seen in non smoker. Large cell carcinoma – 15% : .less well – differentiated. .may occur at any part of the lung. .Tumors are large by the time they are diagnosed. .has greater possibility of spreading to brain and mediastinum. Small cell lung cancer: .small cell lung cancer also called oatcell because SCLC cells have oat grain appearance. .It arises from endocrine cells [kulchitisky cells] where many hormones are secreted .spread to lymph nodes and other organs more quickly than NSCLC . .usually started in one larger breathing tube. .Tend to grow rapidly . .commonly has spread by the time and is considered a systemic disease. .It is the only one of the bronchial carcinomas that respond to chemotherapy presentations: .lung cancer may present in number of different ways