溶血性贫血的介绍.ppt

EnzymopathiesHemolytic Anemia See figure 17-5 Sites of HemolysisHemolytic Anemia Extravascular (See Figure 16.1) Destruction occurs in reticuloendothelial system (mostly the spleen) Hemoglobin released to macrophages Senescent RBC Culling Pitting Sites of Hemolysis Intravascular (See Figure 16.2) Destruction occurs within the blood vessels Hemoglobin is released to the plasma Sites of Hemolysis Factors leading to intravascular hemolysis Complement coating Artificial surfaces Microangiopathic processes Infection Sites of Hemolysis Factors leading to intravascular hemolysis, continued Burns Li