丹芪补肾活血汤联合洛汀新治疗早期糖尿病肾病的临床视察.pdfVIP

提 要 目的：观察丹芪补肾活血汤联合洛汀新治疗早期糖尿病肾病（DN）的疗效和安全 性，探讨其作用机理。 方法：将符合标准的 80 例早期糖尿病肾病患者随机分为对照组 40 例和治疗组 40例，在常规西药治疗基础上，对照组给与洛汀新，治疗组给与洛汀新联合丹芪补 肾活血汤治疗，疗程8周。观察两组治疗前后临床症状、化验室检查指标的变化， 并做统计学分析。 结果：治疗组总有效率为 87.5%，明显高于对照组的 62.5%,（P0.01）；在改 善临床症状、减少尿蛋白、改善血糖、纠正血脂代谢紊乱等方面治疗组均优于对照 组(P＜0.05或P＜0.01)，两组均未发现任何不良反应。 结论：丹芪补肾活血汤联合洛汀新治疗早期DN安全有效，值得临床推广。 关键词：早期糖尿病肾病；丹芪补肾活血汤；中西医结合疗法；临床研究 Observation on Therapeutic Effect of Danqi Bushen Huoxue Decocstion Treatment Combined with Lotensin on Early Diabetic Nephropathy Abstract Objective The purpose of this paper is to observe the therapeutic effects and safety of Danqi Bushen Huoxue Decocstion treatment combined with Lotensin on early diabetic nephropathy (DN), and to further investigate its mechanism. Methods 80 patients with early diabetic nephropathy were randomly divided into control group and treatment group, 40 cases of each group. On the basis of conventional medicine, the patients of the control group were given Lotensin, while the patients of the treatment group were given Danqi Bushen Huoxue Decocstion on the basis of the patients of the control group, 8 weeks for a course of treatment. Their clinical symptoms and related detection indicators in laboratory after treatment were evaluated and compared with those before treatment. Results The total therapeutic effects of the treatment grou