清金止咳汤对COPD急性加重期痰热壅肺证的临床探究.pdfVIP

目 录 中文摘要··················································1 英文摘要··················································3 ，-—J一 ‘j l 置 。。。··。。·。·········································5 正 文··············································．··．7 1．研究对象与方法·······································7 1．病例选择··············································．7 1．2一般资料·········．．···································1O 1．3研究方法···一·········································1 1 1．4观察指标···························-··················12 1．5证候疗效判断标准······································13 1．6观察方法···········································-··14 1．7统计学处理······，··································．··14 2．结 果············-·································14 3．讨 论··············································16 4．存在问题和展望········“·····················．．·．．．28 结 论············!·····································29 参考文献··········································．···．··30 主要英文缩略语表······“··························-···．··33 综 述···········································．···．··35 致 谢··················································52 攻读学位期间发表的学术论文目录····················．···．··53 作者声明······································．···．．．．．．．54 个人简历······································．···．．·．．．．55 中文摘要 目的：本研究通过观察清金止咳汤对慢性阻塞性肺疾病(Chronic ObstructiveDiseaseCOPD)急性加重期痰热壅肺证患者的临 Pulmonary 床疗效及治疗前后肺功能、血气分析的影响，阐明清金止咳汤治疗COPD 急性加重期痰热壅肺证的作用机理，为更有效地治疗COPD提供新的思 路和方法。 方法： 院呼吸内科门诊及病房COPD急性加重期，中医辨证属痰热壅肺证患者， 随机分成治疗组，及对照组。治疗组以常规西医和清金止咳汤治疗，对 照组以常规西医，疗程均为2周。观察治疗前后症状，体征，肺功能， 血气等指标的变化。 结果： 1．在证候疗效方面，治疗组总有效率为92．88％，对照组总有效 要证候(咳嗽、咯痰、喘息、自汗、气短、哮鸣音、发热、胸痛、纳呆) 方面，治疗组明显改善患者的证候，且治疗组疗效明显优于对照组 volumeinone FEVl(forced second，第一秒用力呼气容积)指 expiratory 标治疗前后差异显著(氏0．05)，对照组FEVl指标治疗前后、对照