大脑可塑性与人脑语言中枢的精准定位 - iscslp 2016!.pdfVIP

大脑可塑性与人脑语言中枢的精准定位 Brain Plasticity and Language Processing 谭力海 深圳神经科学研究院 Shenzhen Institute of Neuroscience 1 Neuroplasticity refers to the brains ability to reorganize itself by forming new neural pathways due to changes in behavior, cognition, and environment. 大脑可塑性指大脑为了适应行为、认知和环境的变化，需要 形成新的神经通路，进行自组织的能力。 Children’s brain: highly plastic. Adult patients: plastic (reorganization) Lesion study Male, now age 57 ，car accident at age 32, caused left temporal lobe dsyfunctional Normal people’s language comprehension Right temporal cortex is responsible for his language comprehension Is a normal adult’s brain plastic? Research of the last century: not really; much less plastic. Recent fMRI studies: Normal adults’ brains are plastic too Draganski et al., Nature, 2004 Normal adults subjects learnt a classic three-ball cascade juggling routine for 3 months. Carreiras, Price, et al., Nature, 2009 Members of the guerrilla forces were illiterate but upon putting down their weapons and returning to society, 20 were given an opportunity to learn to read for the first time in their DTI results are that paths early twenties through the corpus callosum region of interest were • 20 late-literates who had identified in left and right completed a literacy angular and dorsal occipital program in adulthood in native tongue (Spanish) gyri that was structurally different in the lat