CLARIFY-2012ESC演讲PPT.pptxVIP

Women and men with stable CAD have similar cardiovascular outcomes: observations from an international prospective cohort of 30 977 patients from 45 countries;Disclosures;Causes of death in women 75 years in Europe;Background;Euro Heart Survey on stable angina Cumulative probability of death or MI in patients with confirmed CAD and stable angina according to gender.; HR 95% CI P Death or MI 2.07 1.16–3.72 0.01 Death or MI, 2.09 1.14–3.85 0.02 adjusted for age, diabetes, LV function, and severity of CAD Death or MI, 2.07 1.14–3.74 0.02 adjusted for age and use of statin and antiplatelet therapy Death or MI, 2.20 1.22–3.98 0.009 adjusted for age and revascularization ;Prognostic Implications of Stable Angina Pectoris Among Women and Men;/ISRCTEnrollment criteria;Aims of this analysis;Population of interest with 1-year follow-up n = 30 977 ;Worldwide distribution;Statistical analysis;Demographics;;Prior Medical history;Symptomatic status;Cardiac parameters and angiographic findings;Cardiovascular treatments;Major 1 year outcomes;Interaction between gender and history of MI/revascularization;Interaction between age and gender;Outcomes in selected subsets;Outcomes in selected subsets;Interpretation;Limitations;Conclusion;Available online now;Backup slides;Death rates in Europe, men and women 75 years of age; /cdv-statistics.html, reprinted with permission from the World Health Organization.;Effect of gender on the investigation and management of new-onset stable angina from the Euro Heart Survey of Stable Angina. ;CI indicates confidence interval. The size of the data markers represents the number of angina cases.*Annual risk per 100 population, using estimated total population of Finland in 1996. Because the case definitions of angina are mutually exclusive, the same population denominator was used for each.?Age-standardized to the combined (women and men) population.;Gender bias in CAD;CAD: if gender matters? ;;M