Rapamycin Induces MAP Kinase Phosphatase (MKP)2-课件.pptVIP

Rapamycin Induces MAP Kinase Phosphatase (MKP)-1Expression Through Activation of ProteinKinase B and Mitogen-activated Protein Kinase Kinase Pathways 臻氟敦棉物凉寓鲜蔬朴按戳锭押蕉姚终足氧军氦焙镑刀啊炕亥板署烯蔚荚Rapamycin Induces MAP Kinase Phosphatase (MKP)2-课件Rapamycin Induces MAP Kinase Phosphatase (MKP)2-课件 Background: MAP kinase phosphatase (MKP)-1 plays a critical role in regulating inflammation in innate and adaptive immunity. Results: mTOR inhibition leads to induction of MKP-1 through the activation of AKT1 and MEK1/MEK2 pathways. Rapamycin pretreatment of macrophages inhibits LPS-mediated p38 activation