低促性腺激素性性腺功能减退的患者中Prader睾丸测量器误差较大.docVIP

低促性腺激素性性腺功能减退的患者中Prader睾丸测量器误差较大 　　摘要：目的 睾丸体积的大小与其功能关系密切，关于Prader睾丸测量器的准确性有争议。本文在低促性腺激素性性腺功能减退（HH）的患者中，对比Prader睾丸测量器及超声两种方法测量睾丸体积的结果，以评估Prader睾丸测量器测量睾丸体积的准确性及其影响因素。方法 对27名低促性腺激素性性腺功能减退的男性患者（平均年龄25±5岁）进行性激素的治疗并长期随访，患者治疗前及每次3个月复诊都接受Prader睾丸测量器及超声两种方法测量睾丸体积，共得到87次测量结果，双侧睾丸一共174组数据。结果 Prader睾丸测量器及超声两种方法测量的睾丸平均体积分别为（7.5±3.6）ml、（3.0±2.1）ml。两种测量方法之间具有相关性（r=0.738，P0.001）。但是Prader测量器测得的睾丸体积平均超过了超声测量结果的（4.5±2.7）ml，相当于超声测量结果的3.2倍。?G丸体积越小，Prader测量器测量结果的误差越大。结论 在HH患者中，使用Prader睾丸测量器测量睾丸体积的误差较大，临床上应仅作为参考。Prader测量器测得的睾丸体积超过实际体积。睾丸体积越大，Prader测量器测得的睾丸体积越接近实际体积。 　　关键词：低促性腺激素性性腺功能减退；Prader睾丸测量器；睾丸体积；超声测量 　　In Patients with Hypogonadotropin-induced Hypogonadism，the Prader Testis has a Greater Error 　　WANG Yu1，WANG Wei2，JI Wen3，HE Wei2，LI Yan-bing4，LIAO Zhi-hong4 　　（1.Department of Internal Medicine，General Hospital of Chinese peoples Armed Police，Shenzhen 518000，Guangdong，China； 　　2.Department of Ultrasound，the First Affiliated Hospital of Sun Yat-sen University，Guangzhou 510080，Guangdong，China； 　　3.Department of Endocrinology，Huzhou Central Hospital，Huzhou 313000，Zhejiang，China； 　　4.Department of Endocrinology，the First Affiliated Hospital of Sun Yat-sen University，Guangzhou 510080，Guangdong，China） 　　Abstract：Objective The relationship between the size of testicular volume and function closely，controversial about the accuracy Prader orchidometer. In hypogonadotropic hypogonadism（HH）in patients with contrast Prader orchidometer and ultrasound two methods of measurement of testicular volume results in accuracy and influencing factors of evaluation of Prader orchidometer the measurement of testicular volume.Methods 27 male patients with lower gonadotropin gonadal hormone of hypogonadism（mean age 25±5 years）for the treatment of sex hormone and long-term follow-up of patients before treatment and every 3 months to accept Prader orchidometer and two ultrasonic method for the measurement of testicular volume，a total of 87 results a total of 174 sets of data，bilateral testes.Results P