老年精神分裂症和Alzheimer氏病患者认知功能的对照研究.PDF

老年精神分裂症和Alzheimer氏病患者认知功能的对照研究.PDF

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老年精神分裂症和Alzheimer氏病患者认知功能的对照研究

·164 · Chinese Jo rnal of Clinical Psychology Vol.9 No.3 2001 Alzheimer ,,,, (中南大学湘雅二医院, 湖南长沙410011) 【】 :Alzheimer ; Alzheimer 。:(MMSE)、 (WMS)、(WCST)、(Alzheimer ), 34 45 (45 ) 、28 Alzheimer 31。: Alzheimer 。 Alzheimer , ; , ,Alzheimer 。 Alzheimer , 。: Alzheimer , 。Alzheimer 。 【】 ;Alzheimer ; :R395.3   :A   :1005-3611(2001)03-0164-04    A Comparative Study on Cognitive Function between Geriatric Schizophrenic and Alzheimers Patients XIAO Zhi-jie, LI Qi -xiang, CHEN Zhao-h o, et al Second Xiangya Hospital, Central So th University, Changsha 4 10011, China 【Abstract】 Objective:The p rpose was to examine ne ropsychological difference between schizophrenia and Alzheimer patients in respect of frontal exec tive f nction and memory f nctions.aswell as their relationship with social f nctional activity.Methods: A total of 93 s bjects participated in this st dy:31 normal control s bjects, 34 geriatric schizophrenic patients with disease onset before the age of 45 years, and 28AD patients.All s bjectswere administered a battery of ne ropsychological tests,which incl ded Wechsler Memory Scale (WMS),Wisconsin Card-sorting Test(WCST), Mini-Mental State Examination(MMSE), and Activity of Daily Living Scale(ADL)Results:Differences in ne ropsychological defficits between schizophrenic and AD patientswere show on WMS and WCST.schizophrenia patients were less impaired with delayed recall b t similar on semantic memory when compared with AD patients.Significant correlationwas fo nd between memory deficits and frontal exec tive f nction among schizophrenic pa- tients.When compared to AD patients, social level compatible with normal controls.Conclusion:The pattern of ne ropaychological defictits in schizophrenia was different from that in progressive cortical

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