基于胸阻抗的人体肺功能参数测量方法-南方医科大学学报.PDF

·1352 · doi 10.3969/j.issn. 1673-4254.2013.09.21 J South Med Univ, 2013, 33(9): 1352-1356 技术方法 基于胸阻抗的人体肺功能参数测量方法基于胸阻抗的人体肺功能参数测量方法 1 1 1 1 2 1 杨建明 ，钟胜河 ，梁妃学 ，郭劲松 ，李伟龙 ，李金明 1 2 南方医科大学基础医学院生物信息学系，广东 广州 510515 ；杨森电子科技有限公司，广东 广州 510515 摘要：目的研制一种基于人体胸阻抗变化的测量，获取人体肺功能参数的新方法。方法 基于生物阻抗法研究用力呼吸过程中 胸阻抗的变化与肺功能参数值的关系，研制了胸阻抗测量仪实验样机，分别采用所研制的实验样机和基于传统流量计进行肺功 能测量的MIR 公司的spirolab Ⅲ肺功能仪，对10例健康人进行对比实验，所测肺功能参数包括：用力肺活量、一秒率和峰值流 量。结果 所测数据均落于其均值的正负两倍标准差范围之内因为两种方法具有较好的一致性。结论 基于生物阻抗法研制的 实验样机所测肺功能参数与市售肺功能仪（基于流量计测量方法）的测量结果有较好的一致性。 关键词：胸阻抗；阻抗变化；用力肺活量；一秒率；峰值流量 A new method for measuring pulmonary function parameters 1 1 1 1 2 1 YANG Jianming , ZHONG Shenghe , LIANG Feixue , GUO Jinsong , LI Weilong , LI Jinming 1Institute of Bioinformatics, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China; 2 Senyang Company Ltd. of Electronics Technology, Guangzhou 510515, China Abstract: Objective To propose a new method for acquiring pulmonary function parameters based on measurement of volume changes of thoracic impedance. Methods We studied the relationship between the volume changes of thoracic impedance and pulmonary function parameters during forced breathing based on bioimpedance measurement, and developed an instrument for measuring thoracic impedance. Using this instrument and a MRI spirolab III lung function test instrument, both based on flowmeter measurement, we measured such pulmonary function parameters including forced vital capacity (FVC), forced expiratory volume in one second/FVC (FEV1/FVC), and peak expiratory flow in 10 healthy volunteers and compared the measurement results. Results The differences in the parameters measured using the two instruments