computational modeling of microabscess formation计算模型的微小脓肿形成.pdfVIP

Hindawi Publishing Corporation Computational and Mathematical Methods in Medicine Volume 2012, Article ID 736394, 16 pages doi:10.1155/2012/736394 Research Article Computational Modeling of Microabscess Formation Alexandre Bittencourt Pigozzo,1 Gilson Costa Macedo,2 Rodrigo Weber dos Santos,1 and Marcelo Lobosco1 1 Graduate Program in Computational Modeling, UFJF, Rua Jose Lourenc¸o Kelmer s/n, Campus Universitario, Bairro Sao Pedro, ´ ´ ˜ 36036-900 Juiz de Fora, MG, Brazil 2 Graduate Program in Biological Sciences, UFJF, Rua Jose Lourenc¸o Kelmer s/n, Campus Universitario, Bairro Sao Pedro, ´ ´ ˜ 36036-900 Juiz de Fora, MG, Brazil Correspondence should be addressed to Alexandre Bittencourt Pigozzo, alexbprr@ Received 29 June 2012; Revised 28 August 2012; Accepted 5 September 2012 Academic Editor: Vladimir Brusic Copyright © 2012 Alexandre Bittencourt Pigozzo et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Bacterial infections can be of two types: acute or chronic. The chronic bacterial infections are characterized by being a large bacterial infection and/or an infection where the bacteria grows rapidly. In these cases, the immune response is not capable of completely eliminating the infection which may lead to the formation of a pattern known as microabscess (or abscess). The microabscess is characterized by an area comprising