住院2型糖尿病患者合并尿路感染危险因素分析-中华老年多器官疾病.docVIP

·临床研究· 住院2型糖尿病患者合并尿路感染危险因素分析 罗明娟1，梁 伟1，王 刚2，万俊杰3，张 咪1，郭敏珊1，曹建芬1，刘春红1，顾建芬1 （香港大学深圳医院：内分泌与代谢科1，肾内科2，病理科3，深圳 518000） 【摘 要】目的 分析内分泌与代谢科住院2型糖尿病患者尿路感染的患病情况及其临床特点，并探讨2 型糖尿病患者合并尿路感染的危险因素。方法 回顾性地分析香港大学深圳医院2013年10月至2014年9月内分泌与代谢科住院的2型糖尿病患者共249例，收集相应临床资料，比较尿路感染组与非感染组患者年龄、性别、体质量指数、糖尿病病程、糖化血红蛋白（HbA1c）、肾小球滤过率、肌酐、尿微量白蛋白/肌酐、24h尿微量白蛋白定量、尿糖等指标的异同，分析2 型糖尿病患者合并尿路感染的危险因素。结果 住院2型糖尿病患者合并尿路感染的患病率为16.1%；年龄、性别、肾小球滤过率、尿微量白蛋白/肌酐、24h尿微量白蛋白定量、肌酐在两组之间差异具有统计学意义（P＜0.05），女性、年龄越大、肾功能越差、尿微量白蛋白越多的患者越易合并尿路感染。而尿糖、糖尿病病程、HbA1c、体质量指数在各组之间差异无统计学意义。logistic回归分析显示性别、肌酐是尿路感染的独立危险因素。结论 2型糖尿病患者合并尿路感染与性别、肌酐相关，女性、肾功能不良的患者是高危人群。 【关键词】糖尿病，2型；尿路感染；危险因素 【中图分类号】 R587.1 【文献标识码】 A 【DOI】 ? Risk factors for urinary tract infection in type 2 diabetes mellitus inpatients LUO Ming-Juan1, LIANG Wei1, WANG Gang2, WAN Jun-Jie3, ZHANG Mi1, GUO Min-Shan1, CAO Jian-Fen1, LIU Chun-Hong1, GU Jian-Fen1 (1Department of Endocrinology and Metabolism, 2Department of Nephrology, 3Department of Pathology, the University of Hong Kong-Shenzhen Hospital, Shenzhen 518000, China) 【Abstract】 Objective To investigate the prevalence of urinary tract infection (UTI) and its risk factors in type 2 diabetes mellitus (T2DM) inpatients. Methods A total of 249 inpatients admitted in our hospital from October 2013 to September 2014 were recruited in this study and retrospectively analyzed. Their clinical data, such as age, gender, body mass index (BMI), duration of diabetes, glycated hemoglobin A1c (HbA1c), estimated glomerular filtration rate (eGFR), serum creatinine, urine microalbumin/creatinine, 24h urine albumin, and urine glucose were collected and compared between those with UTI and without. Results The prevalence of UTI in this cohort of T2DM inpatients was 16.1%. Significant difference was found in the age, gender, eGFR, creatinine, albumin/creatinine ratio (ACR), and 24h urine albumin were significantly different between the 2 groups (P＜0.05). Females, older, worse eGFR, higher ACR and 24h ACR patients were more prone to