a new triterpenoid saponin from pulsatilla cernua一个新三萜皂苷从白头翁cernua.pdfVIP

Molecules 2010, 15, 1891-1897; doi:10.3390/molecule OPEN ACCESS molecules ISSN 1420-3049 /journal/molecules Communication A New Triterpenoid Saponin from Pulsatilla cernua Yajuan Xu 1,3, Lu Bai 1, Yonghong Liu 4, Yue Liu 1, Tunhai Xu 2,*, Shengxu Xie 1, Yunshan Si 1, 1 2 1 Haiou Zhou , Tonghua Liu and Dongming Xu 1 Academy of Traditional Chinese Medicine of Jilin Province, Changchun 130021, China; E-Mail: xyj6492@ (Y.X.) 2 Department of Traditional Chinese Medicine Chemistry, School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100102, China 3 College of Pharmacy, Jilin University, Changchun 130021, China 4 Key Laboratory of Marine Bio-resources Sustainable Utilization, South China Sea Institute of Oceanology, Chinese Academy of Sciences, No. 164 West Xingang Road, Guangzhou 510301, China; E-Mail: yonghongliu@ (Y.L.) * Author to whom correspondence should be addressed; E-Mail: thxu@ Received: 1 February 2010; in revised form: 24 February 2010 / Accepted: 9 March 2010 / Published: 16 March 2010 Abstract: A new triterpenoid saponin was isolated from Pulsatilla cernua, along with eight known triterpenoids and triterpenoid glycosides. The new compound was identified as 3-O-β-D-glucopyranosyl-(1→4)-α-L-arabinopyranosyl-bayogenin-28-α-L- rhamnopyranosyl-(1→4)-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl ester (1) on the basis of 1D, 2D-NMR techniques, including COSY, HMBC, and HMQC