a comparison between two brine shrimp assays to detect in vitro cytotoxicity in marine natural products比较两个盐水虾化验检测海洋天然产物的体外细胞毒性.pdfVIP

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a comparison between two brine shrimp assays to detect in vitro cytotoxicity in marine natural products比较两个盐水虾化验检测海洋天然产物的体外细胞毒性.pdf

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a comparison between two brine shrimp assays to detect in vitro cytotoxicity in marine natural products比较两个盐水虾化验检测海洋天然产物的体外细胞毒性

BMC Biotechnology BioMed Central BMC Biotechnology x 2002, Open Access 2 Methodology article A comparison between two brine shrimp assays to detect in vitro cytotoxicity in marine natural products 1 1 1 José Luis Carballo* , Zaira L Hernández-Inda , Pilar Pérez and María D García-Grávalos2 Address: 1Instituto de Ciencias del Mar y Limnología, UNAM. Estación Mazatlán. Apartado Postal 811. Mazatlán 82000. México and 2Pharma- Mar SA, C/ de la Calera 3, (Tres Cantos, Madrid), España E-mail: José Carballo* - carballo@ola.icmyl.unam.mx; Zaira L Hernández-Inda - zaira@ola.icmyl.unam.mx; Pilar Pérez - pilar@ola.icmyl.unam.mx; María D García-Grávalos - lgarciagravalos@ *Corresponding author Published: 23 September 2002 Received: 26 February 2002 Accepted: 23 September 2002 BMC Biotechnology 2002, 2:17 This article is available from: /1472-6750/2/17 © 2002 Carballo et al; licensee BioMed Central Ltd. This article is published in Open Access: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the articles original URL. Abstract Background: The brine shrimp lethality assay is considered a useful tool for preliminary assessment of toxicity. It has also been suggested for screening pharmacological activities in plant extracts. However, we think that it is necessary to evaluate