原创力文档a retrospective analysis of amputation rates in diabetic patients can lower extremity amputations be further prevented截肢率的回顾性分析糖尿病患者下肢截肢可以进一步阻止了.pdfVIP
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a retrospective analysis of amputation rates in diabetic patients can lower extremity amputations be further prevented截肢率的回顾性分析糖尿病患者下肢截肢可以进一步阻止了
Alvarsson et al. Cardiovascular Diabetology 2012, 11:18 CARDIO
/content/11/1/18 VASCULAR
DIABETOLOGY
ORIGINAL INVESTIGATION Open Access
A retrospective analysis of amputation rates in
diabetic patients: can lower extremity
amputations be further prevented?
1,4* 2 3 1 1
Alexandra Alvarsson , Buster Sandgren , Carl Wendel , Michael Alvarsson and Kerstin Brismar
Abstract
Background: Lower extremity amputations are costly and debilitating complications in patients with diabetes
mellitus (DM). Our aim was to investigate changes in the amputation rate in patients with DM at the Karolinska
University Hospital in Solna (KS) following the introduction of consensus guidelines for treatment and prevention
of diabetic foot complications, and to identify risk groups of lower extremity amputations that should be targeted
for preventive treatment.
Methods: 150 diabetic and 191 nondiabetic patients were amputated at KS between 2000 and 2006; of these 102
diabetic and 99 nondiabetic patients belonged to the catchment area of KS. 21 diabetic patients who belonged to
KS catchment area were amputated at Danderyd University Hospital. All patients’ case reports were searched for
diagnoses of diabetes, vascular disorders, kidney disorders, and ulcer infections of the foot.
Results: There was a 60% reduction in the rate of amputations performed above the ankle in patients with DM
during the study period. Patients with DM who underwent amputations were more comm
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