preparation and characterization of insoluble silk fibroinchitosan blend films的制备和表征不溶性丝绸fibroinchitosan混合的电影.pdfVIP

Polymers 2010, 2, 719-727; doi:10.3390/polym2040719 OPEN ACCESS polymers ISSN 2073-4360 /journal/polymers Article Preparation and Characterization of Insoluble Silk Fibroin/Chitosan Blend Films Mariana Agostini de Moraes, Grinia Michelle Nogueira, Raquel Farias Weska and Marisa Masumi Beppu * School of Chemical Engineering, University of Campinas, UNICAMP, 13083-970, Campinas, SP, Brazil; E-Mails: marimoraes@feq.unicamp.br (M.A.M.); grinia.nogueira@ (G.M.N.); weska@feq.unicamp.br (R.F.W.) * Author to whom correspondence should be addressed; E-Mail: beppu@feq.unicamp.br; Tel.: +55-19-3521-3893; Fax: +55-19-3521-3922. Received: 25 October 2010; in revised form: 26 November 2010 / Accepted: 2 December 2010 / Published: 13 December 2010 Abstract: The aim of this study was to prepare and characterize membranes of silk fibroin (SF) and chitosan (CHI) blends. Moreover, a conformation transition of SF to a more stable form induced by the addition of CHI was verified. Blend membranes were prepared, after pH adjustment, in different ratios, and physical integrity, crystallinity, structural conformation and thermal stability were characterized. The results of crystallographic analysis (XRD) indicated the tendency to higher structural organization caused by the addition of CHI. Fourier transformed infrared spectroscopy (FTIR) showed that SF is present in a more stable form in the presence of a CHI content of only 25 wt%. Thermal analysis indicated