staphylococcus aureus and wegeners granulomatosis金黄色葡萄球菌和韦格纳肉芽肿病.pdfVIP

Available online /content/4/2/077 Commentary Staphylococcus aureus and Wegener’s granulomatosis † ‡ Eliane R Popa*, Coen A Stegeman , Cees GM Kallenberg* and Jan Willem Cohen Tervaert *Department of Clinical Immunology, University Hospital Groningen, The Netherlands †Department of Nephrology, University Hospital Groningen, The Netherlands ‡Department of Clinical Immunology, University of Maastricht, The Netherlands Correspondence: Prof. Dr CGM Kallenberg, Deptartment of Clinical Immunology, University Hospital Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands. Tel: +31 50 3612945; fax: +31 50 3619069; e-mail: c.g.m.kallenberg@int.azg.nl Received: 17 September 2001 Arthritis Res 2002, 4:77-79 Revisions requested: 5 October 2001 This article may contain supplementary data which can only be found Revisions received: 15 October 2001 online at /content/4/2/077 Accepted: 18 October 2001 © 2002 BioMed Central Ltd Published: 26 October 2001 (Print ISSN 1465-9905; Online ISSN 1465-9913) Abstract Wegener’s granulomatosis (WG) is a form of systemic vasculitis. It is characterized by granulomatous inflammation in the upper and lower airways, vasculitis and necrotizing glomerulonephritis, and is strongly associated with antineutrophil cytoplasmic antibodies against proteinase 3. Since the etiology of the disease is not clear, treatment, consisting