原创力文档surface generated acoustic wave biosensors for the detection of pathogens a review生成声表面波生物传感器检测的病原体进行审查.pdfVIP
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surface generated acoustic wave biosensors for the detection of pathogens a review生成声表面波生物传感器检测的病原体进行审查
Sensors 2009, 9, 5740-5769; doi:10.3390/
OPEN ACCESS
sensors
ISSN 1424-8220
/journal/sensors
Review
Surface Generated Acoustic Wave Biosensors for the Detection
of Pathogens: A Review
María-Isabel Rocha-Gaso 1, Carmen March-Iborra 2, Ángel Montoya-Baides 2 and Antonio
Arnau-Vives 1,*
1 Grupo de Fenómenos Ondulatorios, Departamento de Ingeniería Electrónica, Universidad
Politécnica de Valencia, Spain
2 Instituto Interuniversitario de Investigación en Bioingeniería y Tecnología Orientada al Ser Humano,
Universidad Politécnica de Valencia, Spain
* Author to whom correspondence should be addressed; E-Mail: aarnau@eln.upv.es;
Tel.: +34-963 879 600
Received: 31 May 2009; in revised form: 7 July 2009 / Accepted: 14 July 2009 /
Published: 20 July 2009
Abstract: This review presents a deep insight into the Surface Generated Acoustic Wave
(SGAW) technology for biosensing applications, based on more than 40 years of
technological and scientific developments. In the last 20 years, SGAWs have been attracting
the attention of the biochemical scientific community, due to the fact that some of these
devices - Shear Horizontal Surface Acoustic Wave (SH-SAW), Surface Transverse Wave
(STW), Love Wave (LW), Flexural Plate Wave (FPW), Shear Horizontal Acoustic Plate
Mode (SH-APM) and Layered Guided Acoustic Plate Mode (LG-APM) - have
demonstrated a high sensitivity in the detection of biorelevant molecules in liquid med
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