comparison of proliferation and genomic instability responses to wrn silencing in hematopoietic hl60 and tk6 cells核扩散和比较基因组不稳定性反应wrn沉默在造血hl60和tk6细胞.pdfVIP

Comparison of Proliferation and Genomic Instability Responses to WRN Silencing in Hematopoietic HL60 and TK6 Cells ¤ Xuefeng Ren , Sophia Lim, Zhiying Ji, Jessica Yuh, Vivian Peng, Martyn T. Smith, Luoping Zhang* Genes and Environment Laboratory, Division of Environmental Health Sciences, School of Public Health, University of California, Berkeley, California, United States of America Abstract Background: Werner syndrome (WS) results from defects in the RecQ helicase (WRN) and is characterized by premature aging and accelerated tum