conservation and diversification of an ancestral chordate gene regulatory network for dorsoventral patterning保护和多样化的祖先脊索动物的基因调控网络背腹侧的模式.pdfVIP

Conservation and Diversification of an Ancestral Chordate Gene Regulatory Network for Dorsoventral Patterning Iryna Kozmikova, Jana Smolikova, Cestmir Vlcek, Zbynek Kozmik* Institute of Molecular Genetics, Prague, Czech Republic Abstract Formation of a dorsoventral axis is a key event in the early development of most animal embryos. It is well established that bone morphogenetic proteins (Bmps) and Wnts are key mediators of dorsoventral patterning in vertebrates. In the cephalochordate amphioxus, genes encoding Bmps and transc