continuous quinacrine treatment results in the formation of drug-resistant prions连续奎纳克林治疗导致朊病毒耐药的形成.pdfVIP

Continuous Quinacrine Treatment Results in the Formation of Drug-Resistant Prions Sina Ghaemmaghami1,2., Misol Ahn3., Pierre Lessard1,2, Kurt Giles1,2, Giuseppe Legname1,2¤, Stephen J. DeArmond1,3, Stanley B. Prusiner1,2* 1 Institute for Neurodegenerative Diseases, University of California, San Francisco, California, United States of America, 2 Department of Neurology, University of California, San Francisco, California, United States of America, 3 Department of Pathology, University of California, San Francisco, California, United States of America Abstract Quinacrine is a p