depletion of cytotoxic t-cells does not protect nup98-hoxd13 mice from myelodysplastic syndrome but reveals a modest tumor immunosurveillance effect损耗的细胞毒性t细胞不保护nup98-hoxd13小鼠骨髓增生异常综合征,但揭示了一个温和的肿瘤免疫监视作用.pdfVIP

Depletion of Cytotoxic T-Cells Does Not Protect NUP98- HOXD13 Mice from Myelodysplastic Syndrome but Reveals a Modest Tumor Immunosurveillance Effect Sheryl M. Gough, Yang Jo Chung, Peter D. Aplan* Leukemia Biology Section, Genetics Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America Abstract Myelodysplastic syndrome (MDS) and aplastic anemia (AA) patients both present with symptoms of bone marrow failure. In many AA patients, these features are thought to result from an oligoclonal expansion of cyt