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- 2017-09-12 发布于上海
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dynamics of kv1 channel transport in axons动态kv1频道在轴突运输
Dynamics of Kv1 Channel Transport in Axons
Yuanzheng Gu, Chen Gu*
Department of Neuroscience and Center for Molecular Neurobiology, The Ohio State University, Columbus, Ohio, United States of America
Abstract
Concerted actions of various ion channels that are precisely targeted along axons are crucial for action potential initiation
and propagation, and neurotransmitter release. However, the dynamics of channel protein transport in axons remain
unknown. Here, using time-lapse imaging, we found fluorescently tagged Kv1.2 voltage-gated K+
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