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- 2017-09-17 发布于上海
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e2f-1 directly regulates thrombospondin 1 expressione2f-1直接调节血小板反应蛋白- 1的表达
E2F-1 Directly Regulates Thrombospondin 1 Expression
Wei Ji, Wei Zhang, Wuhan Xiao*
Key Laboratory of Biodiversity and Conservation of Aquatic Organisms, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, People’s Republic of China
Abstract
Thrombospondin 1 (TSP1) has been shown to play a critical role in inhibiting angiogenesis, resulting in inhibition of tumor
growth and metastases. To figure out TSP1’s regulators will lead to reveal its biological function mechanistically. In this
study, we show that E2F-1 could activate the transcriptio
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