参附注射液及硫酸镁佐治老年人慢性充血性心力衰竭临床分析.docVIP

参附注射液及硫酸镁佐治老年人慢性充血性心力衰竭临床分析 　［摘 要］ 目的 观察参附注射液和硫酸镁佐治老年人慢性充血性心力衰竭的临床疗效。方法慢性充血性心力衰竭老年患者63例，随机分为对照组31例，治疗组32例。对照组常规给予降压药、强心药和利尿药治疗，治疗组在此基础上静脉滴注参附注射液和硫酸镁注射液，14d为1疗程，比较两组的疗效。 结果 对照组总有效率为71%，治疗组为97%，疗效相差显著（Plt;0.05）;治疗组的心率、左心室射血分数较对照组改善明显（Plt;0.05）。 结论 参附注射液和硫酸镁佐治老年人慢性充血性心力衰竭疗效较好，能较好地改善心功能。 　　［关键词］ 参附注射液;硫酸镁;心力衰竭 　　Comparative study of Shenfu injection combined with magnesium sulfate and conventional therapy in treating chronic congestive heart failure treated in aged patients 　　Abstract:Objective To compare the curative effect of Shenfu injection combined with magnesium sulfate and the conventional therapy in managing the chronic congestive heart failure in aged patients.Methods A total of63aged patients with chronic congestive heart failure were ran-domly divided into experimental group（n=32）and conventional therapy group（n=31，as control）.The patients applied for conventional therapy were employed to hypotensive drug，cardiac tonic and emictory，while the experimental group was added with Shenfu injection and magnesium sul-fate.Results Total effective rate was71%in control group，97%in experimental group（Plt;0.05）.Heart rate and left ventricular ejection frac-tion were improved significantly in experimental group as compared with control group（Plt;0.05）.Conclusion Treating the chronic congestive　heart failure with Shenfu injection and magnesium sulfate can achieve better curative effects and improve the heart function in aged patients. 　　Keywords:Shenfu injection;magnesium sulfate;heart failure 　　老年人慢性充血性心力衰竭是常见病、多发病，可由冠状动脉粥样硬化、高血压、风湿性心脏病等多种疾病诱发所致，现多采用降压、强心和利尿等对症处理方法作常规治疗，疗效有待提高。近年，采用参附注射液和硫酸镁佐治老年人慢性心力衰竭引起了众多医生的关注。因此，有必要对参附注射液和硫酸镁佐治老年人慢性心力衰竭与常规治疗的疗效作一比较。 　　1 资料与方法 　　1.1 临床资料 　　老年人慢性充血性心力衰竭患者63例，随机分为两组，对照组（常规治疗组）31例、治疗组32例。对照组男17例、女14例，年龄62～90岁，平均病程7.4年。基础疾病为冠状动脉粥样硬化性心脏病12例、肺原性心脏病7例、高血压性心脏病6例、老年退行性瓣膜病2例、风湿性心脏病3例、扩张型心肌病1例。按纽约心脏病协会心功能分级:Ⅱ级6例，Ⅲ级13例，Ⅳ级12例;合并房性期前收缩4例，室性期前收缩2例。治疗组男19例，女13例，年龄64～91岁，平均病程7.5年。基础疾病为冠心病13例、肺原性心脏病8例、高血压性心脏病5例、老年性退行性瓣膜病3例、风湿性心脏病2例、扩张型心肌病1例