the mdt-15 subunit of mediator interacts with dietary restriction to modulate longevity and fluoranthene toxicity in caenorhabditis elegans中介的mdt-15亚基与饮食限制调节长寿和荧蒽在秀丽隐杆线虫毒性.pdfVIP

The MDT-15 Subunit of Mediator Interacts with Dietary Restriction to Modulate Longevity and Fluoranthene Toxicity in Caenorhabditis elegans Jennifer Schleit, Valerie Z. Wall, Marissa Simko, Matt Kaeberlein* Department of Pathology, University of Washington, Seattle, Washington, United States of America Abstract Dietary restriction (DR), the limitation of calorie intake while maintaining proper nutrition, has been found to extend life span and delay the onset of age-associated disease in a wide range of species. Previous studies have suggested that DR can reduce the