Applications of Lawesson’s Reagent in Organic and Organometallic Syntheses.pdfVIP

REVIEW 1929 Applications of Lawesson’s Reagent in Organic and Organometallic Syntheses Applications of Lawesson’s Reagent in Organic and Organometallic SynthesesMartin Jesberger,* Thomas P. Davis, Leonie Barner Centre for Advanced Macromolecular Design, School of Chemical Engineering and Industrial Chemistry, The University of New South Wales, Sydney NSW 2052, Australia Fax +61(2 E-mail: camd@unsw.edu.au Received 24 March 2003; revised 24 April 2003 dine and require a large excess of reagent. Furthermore, Abstract: This review, including 245 references, describes the ap- long reaction times are needed; yields are usually low and plication of Lawesson’s reagent [2,4-bis(p -methoxyphenyl)-1,3- 1–4 dithiaphosphetane-2,4-disulfide] LR in organic and organometallic variable. Many research groups have investigated other syntheses. Thionations of carbonyl-containing compounds as well useful thionation reagents as a substitute for phosphorus as unexpected reactions are shown for different applications (e.g. pentasulfide.5–9 In 1956, syntheses of varying aryl thiono- cyclizations, rerrangements, syntheses of heterocyclic compounds phosphine sulfides were described by Lecher et al.10,11 In etc.). Syntheses of novel organometallic compounds by LR are also 1967, Hoffman and Schuhmacher reported on the trans- discussed. formation of benzophenone to thiobenzophenone via 2,4- 1 Introduction