妊娠妇女甲状腺功能减退症及尿碘关系.docVIP

孕妇甲状腺功能减退症与尿碘关系 李建宁1赵迎春1 周黎黎1 何岚2 高显兰3 张永红4 王新荣5 1克拉玛依市中心医院内分泌科（新疆，834000）2西安交通大学第一附属医院内分泌科（陕西710061）3克拉玛依市人民医院妇产科（新疆，834000）4 克拉玛依市中心医院妇产科（新疆，834000）5 独山子石化医院妇产科（新疆，834000） [摘要] 目的：明确孕妇甲状腺功能减退症与尿碘的关系。方法：对266例孕龄妇女及2076例孕妇进行甲状腺功能测、尿碘测定。结果：1）育龄妇女及孕妇甲状腺功能的分布情况为：正常245例（92.1%）、TSH减低3例（1.1%）、甲减18例（6.8%）及正常1836例（88.4%）、TSH减低130例（6.3%）、甲减110例（5.3%）。2)育龄妇女甲减组尿碘显著升高，两组高尿碘的发生率显著性升高。结论：孕龄妇女及孕妇的碘摄入量增加使甲状腺功能减退症的患病率增加。 [关键词]：尿碘 甲状腺功能减退症 孕妇he relationship between hypothyroidism of pregnant woman and the urinary iodine Li Jian-ning1, Zhou Li-li1 , Zhao Ying-chun1, He Lan2, Gao Xian-lan3, Zhang Yong-hong4, Wang Xin-rong5. 1 Endocrine Department, Karamay Zhongxin Hospital（Xinjiang，834000）2 Department, Affiliated Hospital No. 1, Xi’an Jiaotong University（Shanxi, 710061）3 Maternity Department, Karamay Renmin Hospital（Xinjiang，834000）4 Maternity Department, Karamay Zhongxin Hospital（Xinjiang，834000）5 Maternity Department, Dushanzi Hospital（Xinjiang，834000） [Abstract] Objective: To evaluate the relationship between hypothyroidism of pregnant woman and the urinary iodine. Methods: Levels of thyroid hormones and iodine in urine, were measured at 266 cases of gestational age women and 2076cases of pregnant women. Results: 1) Among subjects with normal thyroid function, those with hyperthyroidism and those with hypothyroidism were 245(92.1%), 3(1.1%) and 18(6.8%) at 266 cases of gestational age women, respectively. Among subjects with normal thyroid function, those with hyperthyroidism and those with hypothyroidism were1836（88.4%）, 130（6.3%） and 110（5.3%）at 266 cases of gestational age women, respectively.2) 3) Urinary iodine at 266 cases of gestational age women and incidence of high urinary iodine in two group were significantly increased in hypothyroidism. Conclusion: Excessive iodine intake may lead to hypothyroidism at gestational age of women and pregnant women. 甲状腺功能减退症是妇女的常见病，妊娠合并甲状腺功能减退症可发生严重的围产期并发症如妊娠高血压综合征、低体重儿、早产、流产、胎盘早剥、死胎等，并引起后代智力的下降。现有的研究认为碘摄入过量可能是甲状腺功能减退症的一个重要原因。因此，我们对妊娠的