2010舒血宁注射液对脑缺血再灌注大鼠缺拟血半暗带水通道蛋白1和水通道蛋白9表达的影响.pdfVIP

# 1018# J Apop lexy and Nervou D i ea e, Novem ber 2010, Vol 27, No. 11 : 1003-2754( 20 10) 11-1018-04 1 9 1 1 1 1 2 姜 丹, 李 彬 , 马 军, 陈命家 , 汪 凯 : ( IP) 1( AQP1) 9( AQP9) ( M CAO), 2h, 1d3d7d, SABC AQP1 AQP9 IP, , AQP1 AQP9( P 0. 05 P 0. 01), 1d3d7d, AQP1 AQP9 () (P 0. 05P 0. 0 1) AQP1AQP9, , : ; ; ; 1; 9 : R743 : A Effect of Shuxuening parenteral solution on the expression ofAQP1 andAQP9 protein in ischemicpenumbra after local cerebral ischem ia/reperfusion inMACO rats JIAN G Dan, LI B in, MA Jun, et al. (Dep artm ent of N eurology, X i- nanH osp italAff iliate to A nhuiH ighM e icine Training Schoo,lH ef ei 230031, China) Abstract: Objective T o ob erve the effect of Shuxuen ing parenteral olution on the expre ion of AQP1 and AQP 9 prote in in i chem ic penum bra( IP) after local cerebral i chem ia/reperfu ion in MACO rat . M ethods T he local i- chem ia/ reperfu ion m odelw a e tab li hed by intralum inal thread occlu ion of them iddle cerebral artery(M CAO). T he an-i m al w ere random ly divided into ham group, m odel group, Shuxuening parenteral olution and Chuanx iongq in group. U ing the mi munohi to chem ical techn ique for treptav id in-biotin com plex ( SABC ), the expre ion of AQP 1 and AQP9 w a ob- erved on 1d, 3d and 7d in IP of the cortex of frontal and par ietal lobe. esult T he value and po itive unit of AQP1 and AQP 9 prote in expre ion in m odel group w ere h igher than tho e in ham group in IP of the cortex of fron tal or par ietal lobe after lo cal cerebral i chem ia/reperfu ion