蛇胆苦柏爽肤洗液治疗阴囊湿疹疗效及安全拟性评价.docVIP

蛇胆苦柏爽肤洗液治疗阴囊湿疹疗效及安全性评价 新乡医学院第一附属医院皮肤科 赵香容专家讲座 [摘要] 目的!观察5%蛇胆苦柏爽肤洗液治疗阴囊湿疹的疗效及安全性 方法!将152 例阴囊湿疹患者随机分为3 组 治疗组51 例予5%蛇胆苦柏爽肤洗液外用 对照A 组50 例予5%蛇胆苦柏爽肤洗液的单纯基质外用 对照B 组51 例予曲安奈德益康哇乳膏外用 每日2次井每周递减外用次数 3周后观察疗效井评价其安全性 结果!治疗组治愈率 有效率与对照B 组比较差异无统计学意义 P 0.05 两组疗效相当 治疗组 对照B 组治愈率 有效率与对照A 组比较 差异有统计学意义 P 0.05 3组比较 对照B 组起效时间较短 观察3周结束时各组不良反应发生情况比较 差异无统计学意义 P 0.05 随访显示治疗组复发率较低 P 0.05 结论!5%蛇胆苦柏爽肤洗液治疗阴囊湿疹疗效与曲安奈德益康哇乳膏相当 优于5%蛇胆苦柏爽肤洗液的单纯基质 长期使用复发率低 不良反应较少 Evaluation of efficacy and safety of 5% butyl flufenamate ointment in treating scrotal eczema WANG Yan-yun LI Zhan-guo CHEN Yan-hui SHI Tian-wei ZHANG Min Department of Dermatology the People S HoSpital of Zhengzhou Zhengzhou 450003 China [abstract] Objective: To evaIuate the efficacy and safety of butyI fIufenamate ointment in treating scrotaI eczema. Methods: One hundred and fifty-two patients with scrotaI eczema were randomIy divided into three groups: treatment group and controIs A, B. 51 patients in treated group had taken 5% butyI fIufenamate ointment. 50 patients in controI A were given butyI fIufenamate ointment base. TriamcinoIone acetonide and econazoIe cream was given to 51 patients in controI B. AII creams were appIied twice daiIy for three weeks and appIication freguency graduaIIy reduced during the treatment. Results: There was no difference in cure rate and effective rate between treated group and controI B (P 0.05). The cure rate and effective rate in controI A differed significantIy from both treated group and controI B (P 0.05). Treatment with triamcinoIone acetonide and econazoIe cream showed effect sooner than with other two creams. No difference in adverse effects was observed among three groups. FoIIow-up showed Iower recurrence rate in group treated with 5% butyI fIufenamate ointment. Conclusions: 5% butyI fIufenamate ointment and triamcinoIone acetonide and econazoIe cream have comparative effectiveness with fewer adverse effects and Iower recurrence rate in treating scrotaI eczema. [key words] scrotaI eczema; b