氟代脱氧葡萄糖正电子发射计算机断层显像在原发性肝细胞肝癌诊治.pdfVIP

• 480 • Journal of Biomedical Engineering, Jun. 2017, Vol. 34, No.3   ·综 述· 18氟-氟代脱氧葡萄糖正电子发射计算机断层 显像在原发性肝细胞肝癌诊治中的研究与 应用 王微    综述    游金辉    审校 川北医学院附属医院 核医学科 （四川南充   637000 ） 18 【摘要】   肝细胞肝癌为常发癌症，发现时多属中晚期，进展快，治疗效果差，死亡率高。 氟-氟代脱氧葡 18 萄糖正电子发射计算机断层显像（ F-FDG PET/CT ）能够发现早期病灶，对肝细胞肝癌患者的诊断、治疗及预后 有着重要影响，尤其是在对转移灶的检出和复发的监测等方面具有明显优势。但 18F-FDG PET/CT 显像存在肝细 胞肝癌显像效果欠佳、诊断率较低等不足，充分认识 18F-FDG PET/CT 显像的优势和局限性，才能够为肝细胞肝癌 患者提供更好的临床诊断和治疗依据。本文就 18F-FDG PET/CT 显像在肝细胞肝癌诊治中的研究与应用作一简要 介绍。 18 【关键词】  原发性肝细胞肝癌； 氟-氟代脱氧葡萄糖；正电子发射计算机断层显像；诊断 Research and application of 18F-fluorodeoxyglucose positron emission tomography/ computed tomography for the diagnosis and treatment of primary hepatocellular carcinoma WANG Wei, YOU Jinhui Department of Nuclear Medicine, the Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan 637000, P.R.China Corresponding author: YOU Jinhui, Email: youjh@126.com 【Abstract 】 Primary hepatocellular carcinoma is a common cancer. Many patients are found with intermediate- advanced stage, rapid development, poor treatment and high mortality. 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) can discover the early lesions and therefore plays an important role in diagnosis, treatment and prognosis of patients with hepatocellular carcinoma. It especially has obvious advantages in detecting metastasis and monitoring recurrence. However, 18F-FDG PET/CT imaging has poor quality and low diagnosis rate. Understanding the advantages and limitations of 18F-FDG PET/CT can provide better basis for clinical diagnosis and treatment for hepatocellular carcinoma patients. This article briefly introduces the research and ap