子宫内膜癌宫颈间质浸润临床病理特征-tumor.pdfVIP

260 　　肿瘤2014 年3 月第34 卷第3 期　TUM OR Vol. 34, March 2014 DOI: 10.3781/j .issn.1000-7431.2014.03.010 Copyright© 2014 by TUM OR Clinical Research 临床研究· 子宫内膜癌宫颈间质浸润临床病理特征 姚　兰，程建新，王建英 河北医科大学第四医院妇科，河北石家庄　050011 [摘要]　目的：探讨子宫内膜癌宫颈间质浸润的临床病理特征。方法：回顾性分析 2012 年 1 月—2012 年 12 月具 备完整病历资料的2 13 例子宫内膜癌患者的临床病理资料，评估子宫内膜癌宫颈间质浸润相关危险因素。结果： 2 13 例子宫内膜癌患者中，宫颈间质浸润 71 例 （33.3% ）。单因素分析发现，年龄、体质量指数、空腹血糖、血清 P ＞ 0.05 ），而组织学分级、肌层浸润、 总胆固醇、术后病理以及是否合并子宫肌瘤与宫颈间质浸润无明显相关性 （ 病变范围以及是否存在脉管癌栓与宫颈间质浸润相关 （ P ＜ 0.05 ）。多因素分析结果显示，组织学分级和病变范围 是子宫内膜癌宫颈间质浸润的独立危险因素。磁共振成像诊断子宫内膜癌宫颈间质浸润的敏感度、特异度和准确 性均优于经阴道超声检查。结论：组织学分级和病变范围是子宫内膜癌宫颈间质浸润的独立危险因素。在预测子 宫内膜癌宫颈间质浸润方面，磁共振成像较经阴道超声检查更为可靠。 [关键词]　子宫内膜肿瘤；宫颈间质浸润；诊断 [中图分类号]　R737.3 [文献标志码] A [文章编号]　1000-7431 (2014) 03-0260-04 Clinicopathologic features of endometrial carcinoma with cervical interstitial invasion YAO Lan, CHENG Jian-xin, WANG Jian-ying Department of Gynaecology, Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, Hebei Province, China [A BSTRACT]　Objective: To investigate the clinicopathologic features of endometrial carcinoma patients with cervical interstitial invasion. Methods: The clinical data from 213 endometrial carcinoma patients with complete medical records admitted from January 2012 to December 2012 were retrospectively analyzed. The potential risk factors for cervical interstitial invasion were evaluated. Results: Among these 213 patients, 71 (33.33%) had cervical interstitial invasion. Univariate analysis found that the factors including age, body mass index, fasting blood glucose level, serum cholesterol level, postoperative pathology, and uterine myoma were not associated with cervi