2016版肺癌免疫学治疗.pptxVIP

肺癌的免疫学治疗Immunotherapy in the Treatment of Lung Cancer淮安市第一人民医院 呼吸内科 陈 炜CONTENTS肺癌免疫学治疗的背景01check-point inhibitor免疫治疗02其他针对肺癌的免疫学治疗进展03肺癌免疫学治疗的展望04六大特征十大特征维持增殖信号失去生长抑制抵抗细胞死亡复制的永生化基因组不稳定和突变促肿瘤的炎症诱导血管形成侵袭和转移Hallmarks of Cancer新增4个特征The hallmarks of cancer. Cell. 2000Hallmarks of cancer: the next generation.Cell. 2011Robert A. Weinberg （A Founding Member of the Whitehead Institute for Biomedical Research and Professor of Biology at the Massachusetts Institute of Technology）逃避免疫摧毁细胞能量失常TCR or CAR genetic engineeringT cell cloning肿瘤免疫治疗方式CD40Peptide vaccineDC vaccineGenetic vaccineT 细胞第二信号CD137