血脂治疗新进展.pptVIP

临床血脂的现状 强调对高危人群的积极降胆固醇治疗。 LDL-C尽可能降至低些。 降脂药物应坚持长时间服用。 SATURN研究点评 动脉粥样硬化疾病进展与LDL之间的相关性 以IVUS作为检测手段，以斑块负荷为替代终点的研究对于临床实践的价值 现有证据表明 人体内动脉粥样硬化斑块可消退 斑块变化与血浆LDL-C浓度密切相关 他汀通过大幅度降低LDL-C可阻断或逆转斑块发展 如何选择他汀？ 降脂疗效 安全性评价 费用 * Finally, we assessed the percentage of change in LCBI. We found dramatic reductions in percent LCBI between standard and aggressive treatment groups. LCBI was reduced by 27% per lesion, 25% per 10mm and 22% per 4mm. * * The relationship between benefit and risk is a key consideration when assessing any drug. This slide shows available doses for the available statins, expressing per