卒中后痫性发作及卒中后癫痫研究现状与进展-中国卒中杂志.PDFVIP

中国卒中杂志 2017年3月 第12卷 第3期 251 ·专题综述· 卒中后痫性发作及卒中后癫痫 研究现状与进展 郭毅佳，何俐，周东 【摘要】 卒中后痫性发作和卒中后癫痫的定义尚不统一，流行病学研究显示其发生率在卒中患者中 作者单位 为3%～30%，对卒中患者的预后有一定的影响。针对卒中后痫性发作和卒中后癫痫的治疗有卒中的治 610000 成都 疗和二级预防以及抗癫痫药物治疗，有的研究显示新型抗癫痫药物的治疗效果优于传统药物，他汀 四川大学华西医院神经 内科 类药物也可能降低其发生率。目前尚缺乏关于卒中后痫性发作和癫痫的诊疗共识或指南，亟待进一步 通信作者 研究为其提供循证医学证据。 何俐 【关键词】 卒中；痫性发作；癫痫；治疗；预后 heli2003new@126.com 【DOI】 - 10.3969/j.issn.1673 5765.2017.03.011 Research Status and Advances of Post-stroke Seizure and Post-stroke Epilepsy GUO Yi-Jia*, HE Li, ZHOU Dong. *Department of Neurology, West China Hospital, Sichuan University, Chengdu 610000, China Corresponding Author:HE Li, E-mail:heli2003new@126.com 【 】 Abstract Definition of post-stroke seizure and epilepsy remains inconsistent so far. The reported incidence of seizures after ischemic infarction varies greatly from 3% to 30%, which may exert adverse effects on clinical prognosis in stroke patients. The intervention strategies include management of stroke risk factors, stroke recurrence prevention and antiepileptic treatment. Some studies indicated that the effect of new antiepileptic drugs was superior to traditional medications, and statins might also lower the risk of occurrence. For now, there is no definite consensus or guideline for the diagnosis