TMS临床治疗分类汇总表.doc

Supplementary Table 1 Noninvasive brain stimulation and chronic pain.a Reference Stimulation site Stimulation parameters Study Design N Pain etiology Outcome measures Conclusions Lefaucheur et al. (2001)1 M1 corresponding to the painful area 10Hz, 1000 pulses, 80% MT, one session Crossover 14 Trigeminal neuralgia, thalamic stroke Visual analog scale Significant but transient reduction in pain Lefaucheur et al. (2001)2 M1 corresponding to the painful area 10Hz and 1Hz, 1000 pulses, 80% MT, one session Crossover 18 Thalamic stroke, brainstem lesion, brachial plexus lesion Visual analog scale Significant but transient reduction in pain only after 10 Hz rTMS Canavero et al. (2002)3 M1 corresponding to the painful area 0.2Hz, 20 pulses, 100% machine output, one session Not reportedb 9 Brain ischemia, spinal cord injury or syringomyelia Visual analog scale, numerical rating scale Mixed results, 3/9 patients reported significant pain relief for not more than 16 hours. The rTMS pain relief was also strongly correlated with propofol-induced pain relief. Brighina et al. (2004)4 Left dorsolateral prefrontal cortex 20Hz, 400 pulses, 90% MT, 12 sessions, one every other day Parallel 11 Chronic migraine Number of migraine attacks, number of ingested pills Significant long-term reduction in both number of headaches and amount of medicine ingested; effects lasted for at least 2 months after treatment Lefaucheur et al. (2004)5 M1 corresponding to the painful area 10Hz, 1000 pulses, 80% MT, one session Crossover 60 Thalamic stroke, brainstem lesion, brachial plexus lesion, spinal cord lesion, trigeminal nerve lesion Visual analog scale Significant but transient reduction in pain Pleger et al. (2004)6 M1 hand area 10Hz, 120 pulses, 110% MT, one session Crossover 10 Minor trauma, radial fracture, luxation of 2nd and 3rd fingers, fracture of navicular bone Visual analog scale Reduction in pain for 45 minutes Khedr et al. (2005)7 M1 corresponding to the painful area 20Hz, 20