养阴疏肝汤对乳腺癌内分泌治疗后类围绝经期综合征的干预.docVIP

精品论文 参考文献 养阴疏肝汤对乳腺癌内分泌治疗后类围绝经期综合征的干预 姜毅1 (通信作者) 盛丽娜1 佘茁萃1 刘焕玲2 　　（1云南省中医医院 云南 昆明 650021） 　　（2云南省第一人民医院 云南 昆明 650032） 　　【摘要】目的：观察养阴疏肝汤对乳腺癌内分泌治疗后引起的类围绝经期综合征的临床疗效。方法：43例内分泌治疗后出现类围绝经期综合征且中医辨证分型为肾阴亏虚、肝郁气结的乳腺癌患者，随机分为治疗组23例，对照组20例，治疗组用中药养阴疏肝汤，随症加减，每日1剂，对照组给谷维素20mg，3次/日, VitB120mg，3次/日；两组均2周为1疗程，共2个疗程。观察治疗前后临床症状、生活质量、激素水平等相关指标的变化。结果：对照组有效率63.5%，治疗组有效率85.2%；两组潮热汗出、倦怠乏力、头痛等症状均较治疗前显著缓解（P﹤0.01），但治疗组优于对照组（P﹤0.05）；卡氏生活质量评分两组均得到提高（P﹤0.05），但治疗组优于对照组（P﹤0.05）；两组治疗前后的激素水平无明显差异（P﹥0.05）。结论：养阴疏肝汤可改善乳腺癌内分泌治疗后引起肾阴亏虚、肝郁气结型类围绝经期综合征患者潮热汗出、抑郁烦躁、倦怠乏力等症状；提高患者生活质量，但对患者激素水平无明显影响。 　　【关键词】养阴疏肝汤；乳腺癌内分泌治疗；类围绝经期综合征；肾阴亏虚；肝郁气结 　　【中图分类号】R271 【文献标识码】A 【文章编号】2095-1752（2015）05-0024-03 　　Yin liver soup for endocrine therapy of breast cancer after the intervention of perimenopausal syndrome Jiang Yi, Sheng Lina, She Zhuocui. The Hospital of traditional Chinese Medicine in Yunnan Province, Kunming 650021, China; Liu Huanling. The First Peoples Hospital of Yunnan Province, Kunming 650032, China 　　【Abstract】Objective Observe Yin liver soup class caused by endocrine therapy of breast cancer after the clinical efficacy of perimenopausal syndrome. Methods 43 cases of endocrine therapy after class and perimenopausal syndrome of traditional Chinese medicine for kidney Yin deficiency, liver depression of breast cancer patients, 23 cases were randomly divided into treatment group and control group 20 cases. Results The control effectiveness 63.5%, treatment group effective rate was 85.2%; Two groups of symptoms such as hot flashes sweat out, languid, headache was significantly alleviate the (P ﹤ 0.01), but the treatment group is better than that of control group (P ﹤ 0.05). Conclusions Yin liver soup can improve endocrine therapy of breast cancer after cause kidney Yin deficiency, liver depression qi junction type perimenopausal syndrome patients with hot flushes the symptom such as sweat, depressed be agitated, languid; Improve the patients quality of life, but had no significant e