刷牙诱导癫二例报告并文献复习.pdfVIP

中国现代神经疾病杂志 年 月第 卷第 期 2014 12 14 12 ChinJContempNeurolNeurosurg,December2014,Vol.14,No.12 ·1087 · 癫 基础与临床研究· · 刷牙诱导癫 ：二例报告并文献复习 周春雷 罗晶 李晓民 王艳 赵德明 【摘要】 目的 探讨刷牙诱导癫 的诱发因素、临床表现、治疗及预后。方法与结果 2例患者系 同胞姊妹，均为刷牙诱导癫 发作，表现为口面部抽搐、单侧上肢抽搐伴意识丧失，数分钟后恢复，例伴1 舌咬伤，神经系统检查正常。头部MRI无异常，脑电图 例正常、例呈现发作间期尖 慢复合波。均未1 1 ⁃ 行抗癫 药物治疗，嘱其避免用力刷牙、缩短刷牙时间后完全控制发作。结论 刷牙诱导癫 是一种少 见的反射性癫 ，癫 发作与刷牙呈锁时关系，轻症患者降低刺激强度即可完全控制发作。 【关键词】 癫 ，反射性； 刷牙 Toothbrushing inducedepilepsy:twocasesreportandreviewofliterature⁃ ZHOUChun⁃lei,LUOJing,LIXiao⁃min,WANGYan,ZHAODe⁃ming1 2 1 1 1 1Department of Neurology, Huaibei Peoples Hospital, Huaibei 235000, Anhui, China 2Department of Neurology, the First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China Corresponding author: ZHOU Chun lei (Email: zhouchunlei001@126.com) ⁃ 【 】 Abstract Objective To discuss the major indicing factors, clinical features, therapy and prognosis of toothbrushing ⁃ induced epilepsy. Methods The clinical manifestations, auxiliary examinations, treatment and prognosis were studied in 2 patients of toothbrushing⁃induced epilepsy, and relatedliteratureswerereviewed. Results Twosisterswithtoothbrushing⁃inducedepilepsywererecruited in our study. Seizures began with facial numbness and convulsive tic, then involving right arm tic, and followed by loss of consciousness. One case was associated with tongue bite. They recovered after a few minutes without administration of any antiepileptic drugs (AEDs). Physical and neurological examination andbrain MRIscan werenormal. ProlongedvideoEEG(VEEG)recordingsduringwakefulnessandsleep showed normalin the oldersister,and spike⁃slow wavesin the youngersister. After brushing theirteeth lessvigorouslyinshortertime