探讨采用小剂量螺内酯治疗冠心病慢性心力衰竭的疗效.docVIP

精品论文 参考文献 探讨采用小剂量螺内酯治疗冠心病慢性心力衰竭的疗效 克东县中医院 164800 【摘 要】目的 研究分析采用小剂量螺内酯治疗冠心病慢性心力衰竭的临床效果观察。方法 此次研究的对象是选择在2010年3月—2015年10月收治的冠心病慢性心力衰竭患者100例，将其临床资料进行回顾性分析，并分为两组，对照组和实验组，每组50例患者，对照组使用中等剂量的螺内酯（25 mg/d）进行冠心病慢性心力衰竭治疗，实验组采用小剂量的螺内酯（10 mg/d）进行治疗。观察两组患者的治疗效果。结果 对照组患者的治疗有效率为94.0%，实验组患者的治疗有效率为96.0%，两组之间比较差异无统计学意义（Pgt;0.05）。在两组患者的并发症发生情况比较，实验组患者的并发症发生率要低于对照组，两组之间差异具有统计学意义（Plt;0.05）。结论 小剂量螺内酯治疗冠心病慢性心力衰竭的效果显著，并发症发生率小，有效改善心功能，值得临床推广和使用。 【关键词】螺内酯；冠心病；慢性心力衰竭；临床效果 [Abstract] Objective To study the clinical effect analysis of low dose spironolactone in treatment of coronary heart disease with congestive heart failure. Methods the study object is selected in 100 patients from March 2010 to October 2015 of coronary heart disease in patients with chronic heart failure，their clinical data were retrospective analysis，and divided into two groups，the control group and the experimental group，50 cases in each group. The control group in the treatment of chronic heart failure of coronary heart disease with moderate doses of spironolactone（25 mg / D）and experimental group using small dose of spironolactone（10 mg / D）treatment. Observe the therapeutic effect of the two groups of patients. Results the effective rate of treatment in the control group was 94%，the effective rate of treatment group was 96%，and there was no significant difference between the two groups（Pgt;0.05）. The incidence of complications in the two groups was lower than that in the control group，the difference between the two groups was statistically significant（Plt;0.05）. Conclusion small dose of spironolactone in the treatment of chronic heart failure of coronary heart disease has significant effect，complication rate，effectively improve heart function，worthy of clinical promotion and application. [keyword] spironolactone；coronary heart disease；chronic heart failure；clinical effect 该研究该院2010年3月—2015年10月收治的冠心病慢性心力衰竭患者100例，采用不同剂量的螺内酯进行治疗的效果。而慢性心力衰竭为临床常见疾病，其临床症状主要表现为呼吸急促、乏力及体液储溜等症状[1]。其病理原因为心脏收缩和舒张功能不全、重要器质性供血障碍引发。临床研究证明[2]